software for OS X

$ = requires key for unimpeded operation

sources

MacUpdate | VersionTracker
reviews and links to popular software updates
HyperJeff
database of OS X software (comprehensive and unusual)
GNU OS X Archive
GNU unix software ported to OS X and packaged for use with the Apple Installer
MacPorts | Fink
package management systems for open-source unix software ported to OS X

utilities

LaunchBar
$ : very useful, quick, configurable keyboard access to find/open/manipulate files/programs (free alternatives: Butler, Quicksilver)
Butler
provides many useful features but I use it simply for it’s excellent multiple clipboard/pasteboard support
OnMyCommandCM
make your own system-wide contextual menu commands
Pixture Studio
excellent contextual menu plugins (PhotoToolCM, QuickImageCM, QuickPlayCM, CalculateSizeCM)
TextExpander
$ : use abbreviated triggers to insert predefined text snippets, and more (preferred over TypeIt4Me)
DEVON technologies
useful service modules (CalcService, WordService)
MenuMeters
CPU/memory/disk/network info in menubar
MenuCalendarClock
$ : replaces menubar clock; includes a drop-down calendar with links to iCal (it remains useful without key)
DiskWarrior
$ : repairs HFS+ volumes (where others fail or make matters worse)
ClamXav
virus scanner (GUI for the ClamAV open source antivirus engine)

if you use a portable

SideTrack
$ : configure trackpad for scrolling and button areas
DoubleCommand
remap keyboard (e.g. remap that useless “enter” key to “option”)
Screen Spanning Doctor
firmware patch allows many iBook/iMac/eMac models to drive external displays separately (like PowerBooks do, without mirroring)
Anacron
automatically runs regular maintenance procedures which are not run if the computer is turned off (or sleeping) at night; this is not needed for 10.5 (Leopard) or newer

network

Little Snitch
$ : internal firewall (for detection/prevention of network connections from the inside out)
VNC client & server
excellent protocol for remote GUI display/control (developed by AT&T); use TightVNC for MSWin and unix
CyberDuck
FTP and SFTP client
NetNewsWire
$ : RSS/RDF client (free “Lite” version also available)
PithHelmet
if you use Safari; a potent content filter to remove advertising and more…
Saft
$ : adds many useful/missing features to Safari, especially: state persistence (windows/tabs which are open when Safari quits/crashes will be renewed at next launch); Safari is not useful to me without these essential features
browser plugins
fast and clean solution for PDF and MS Word files
Adium X
instant-messaging client supporting most protocols (AIM, ICQ, MSN, &c.)
Meteorologist
current weather information and forecasts in dock or menu bar (supports cities around the world)
RadioRecorder
saves network audio streams to MP3 files (CLI version: StreamRipper; also available from MacPorts)

programming

HexEdit
hexadecimal file editor
skEdit
$ : a promising text editor with (X)HTML & CSS tools, excellent extensibility, and SFTP integration
AppKiDo
efficient browser/interface for the Cocoa reference documentation (installed with Developer Tools)

media (audio/video/&c.)

VLC | MPlayer OS X
multimedia players for various audio and video formats including most Windows Media files
Flip4Mac WMV
QuickTime component to play Windows Media video and audio files
Perian
QuickTime component that adds native support for many popular video formats
Cog | Play
audio players that support many file formats (which iTunes & QuickTime neglect)
Max
for creating high-quality audio files in various formats (such as FLAC), from compact discs or files

unfiled

cocoAspell
augment Apple’s spelling service (use dictionaries for many unsupported languages, including improved English dictionaries)
DICTatoro
complete offline dictionary (DICT) solution (installer package includes server, dictionaries, reader); note: Tiger includes a dictionary, though the source is different
SmallScreenX
for previewing windows at smaller screen sizes
MConvert
$ : unit conversion utility (alternative: try the units command in the Terminal)
VoodooPad
$ : powerful personal notepad with wiki-like page creation/linking, object embedding, integrated sketch, and more